Team Leader: Satoru Shinkuma,
Dr. Shota Takashima, a graduate course student, and I started the Shinkuma Laboratory in April 2015. Our team researches gene therapies and protein replacement thera-pies for hereditary skin disorders such as epidermolysis bullosa and congenital hypotrichosis. We’ve been develop-ing regenerative therapies, too. We put most of our efforts into developing gene/regenerative therapies in which gene editing techniques using the CRSPR/Cas9 system, which I learned during my study at Columbia University, are com-bined with iPS techniques.
I’m also in charge of the Epidermolysis Bullosa Analysis Team, which had been handed down from Professor Hiroshi Shimizu to Professor Daisuke Sawamura and on to Senior Associate Professor Wataru Nishie. With guidance and technical support from Professor Shimizu, Senior Associate Professor Nishie and Instructor Hideki Nakamura, I’ve been conducting the classification of disease types in definitive diagnoses using immunohistochemical tests, electron microscopic tests, and genetic tests. I’ll continue to diagnose the disease types of epidermolysis bullosa patients who are referred by medical institutions throughout Japan.
I’d been conducting research under the instruction of Professor Riichiro Abe and Senior Assistant Professor Wataru Nishie. With help from many people, I’m now working on my own team. I’d like to thank all those who’ve been helping me in many ways. Dr. Shota Takashima has been working hard in his research under my inexperienced guidance. Lab tech Kanako Oyama helped me in many experiments, including with gene analysis, even though she was in the lab only one year. And Yui Shinkuma is working hard as a present lab tech.
Download 'The first laboratory' in the annual report 2016, (, 2 pages total: 1.22MB)