Faculty

• UJIIE Hideyuki

  Professor and Chair

  Fields of specialty

  Autoimmune blistering diseases, Atopic dermatitis, Skin immunology

  More

  Certification

  Board Certification by Japanese Dermatological Association

  Professional Societies

  The Japanese Dermatological Association (Delegate and Guideline Committee Member)
  The Japanese Society for Investigative Dermatology (Councilor)
  Japan Organization of Clinical Dermatologists
  Japanese Society for Immunology
  Japanese Society of Allergology (Hokkaido Branch Councilor)
  The Japanese Society for Cutaneous Immunology and Allergy (Delegate and Guideline Committee Member)
  Japanese Society for Psoriasis Research (Councilor)
  Society for Investigative Dermatology
  European Society for Dermatological Research

  Education and professional experience

  2002 Mar M.D., Hokkaido University School of Medicine
  2002 May Resident, Dermatology Dept., Hokkaido Univ. Hospital
  2005 Apr Resident, Dermatology Dept., Hokkaido Cancer Center
  2010 Mar Ph.D., Dermatology Dept., Graduate School of Medicine, Hokkaido University
  2010 Apr Assistant professor, Dermatology Dept., Hokkaido Univ. Hospital
  2012 Sep Visiting fellow, National Institutes of Health (NIH) (Ethan Shevach Lab., USA)
  2013 Apr JSPS Overseas Research Fellowship
  2014 Sep Assistant professor, Dermatology Dept., Hokkaido Univ. Hospital
  2016 Sep Associate professor, Dermatology Dept., Hokkaido Univ. Hospital
  2021 Jan Professor and chairman, Dermatology Dept., Faculty of Medicine and Graduate School of Medicine Hokkaido University

  Major Publications

  1. Muramatsu K, Zheng M, Yoshimoto N, Ito T, Ujiie I, Iwata H, Shimizu H, Ujiie H:
     Regulatory T cell subsets in bullous pemphigoid and dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid.
     J Dermatol Sci 100: 23-30, 2020.
  2. Ujiie H, Iwata H, Yamagami J, Nakama T, Aoyama Y, Ikeda S, Ishii N, Iwatsuki K, Kurosawa M, Sawamura D, Tanikawa A, Tsuruta D, Nishie W, Fujimoto W, Amagai M, Shimizu H, Committee for Guidelines for the Management of Pemphigoid Diseases (Including Epidermolysis Bullosa Acquisita):
     Japanese guidelines for the management of pemphigoid (including epidermolysis bullosa acquisita).
     J Dermatol 46: 1102-1135, 2019.
  3. Ujiie H, Yoshimoto N, Natsuga K, Muramatsu K, Iwata H, Nishie W, Shimizu H:
     Immune reaction to type XVII collagen induces intramolecular and intermolecular epitope spreading in experimental bullous pemphigoid models.
     Front Immunol 10: 1410, 2019.
  4. Ujiie I, Ujiie H, Iwata H, Shimizu H:
     Clinical and immunological features of pemphigus relapse.
     Br J Dermatol 180: 1498-1505, 2019.
  5. Muramatsu K, Ujiie H, Kobayashi I, Nishie W, Izumi K, Ito T, Yoshimoto N, Natsuga K, Iwata H, Shimizu H:
     Regulatory T-cell dysfunction induces autoantibodies to bullous pemphigoid antigens in mice and human subjects.
     J Allergy Clin Immunol 142: 1818-1830, 2018.
  6. Ujiie H, Muramatsu K, Mushiroda T, Ozeki T, Miyoshi H, Iwata H, Nakamura A, Nomoto H, Cho KY, Sato N, Nishimura M, Ito T, Izumi K, Nishie W, Shimizu H:
     HLA-DQB1*03:01 as a biomarker for genetic susceptibility to bullous pemphigoid induced by DPP-4 inhibitors.
     J Invest Dermatol 138: 1201-1204, 2018.
  7. Sasaoka T^#, Ujiie H^#, Nishie W, Iwata H, Ishikawa M, Higashino H, Natsuga K, Shinkuma S, Shimizu H:
     Intravenous IgG reduces pathogenic autoantibodies, serum IL-6 levels, and disease severity in experimental bullous pemphigoid models.
     J Invest Dermatol 138: 1260-1267, 2018. ^# co-first author
  8. Ujiie H, Shevach EM:
     gdT cells protect liver and lung of mice from the autoimmunity induced by scurfy lymphocytes.
     J Immunol 196: 1517-1528, 2016.
  9. Ujiie H, Sasaoka T, Izumi K, Nishie W, Shinkuma S, Natsuga K, Nakamura H, Shibaki A, Shimizu H:
     Bullous pemphigoid autoantibodies directly induce blister formation without complement activation.
     J Immunol 193: 4415-4428, 2014.
  10. Ujiie H, Shibaki A, Nishie W, Sawamura D, Wang G, Tateishi Y, Li Q, Moriuchi R, Qiao H, Nakamura H, Akiyama M, Shimizu H:
      A novel active mouse model for bullous pemphigoid targeting humanized pathogenic antigen.
      J Immunol 184: 2166-2174, 2010.

  Publication Lists (PubMed)

• NATSUGA Ken

  Senior Associate Professor

  Fields of specialty

  Epidermolysis bullosa, Psoriasis, Epidermal stem cells

  More

  Certification

  Ph.D., Hokkaido University Graduate School of Medicine, Japan (2010)
  Board Certification by Japanese Dermatological Association (2008)
  M.D., Hokkaido University School of Medicine, Japan (2003)

  Professional Societies

  The Japanese Dermatological Association
  The Japanese Society for Investigative Dermatology (2020-2023 Junior Board Director, 2022-Diversity Committee Member)
  Japan Organization of Clinical Dermatologists
  European Society for Dermatological Research
  Society for Investigative Dermatology
  Japan Skin Research Club (Organizer)
  The Japan Society of Human Genetics
  Japanese Society of Vitiligo
  Japanese Society for Psoriasis Research

  Education and professional experience

  2003 Mar M.D., Hokkaido University School of Medicine
  2003 Mar Resident, Dermatology Dept., Hokkaido Univ. Hospital
  2005 Apr Resident, Dermatology Dept., Hokkaido Cancer Center
  2006 Apr Medical staff, Dermatology Dept., Hokkaido Univ. Hospital
  2010 Mar Ph.D., Dermatology Dept., Graduate School of Medicine, Hokkaido University
  2010 Sep Visiting Scientist, Cancer Research UK Cambridge Research Institute (Fiona Watt Lab., UK)
  2011 Apr JSPS Overseas Research Fellowship
  2012 Sep Assistant professor, Dermatology Dept., Graduate School of Medicine, Hokkaido University
  2016 Aug Associate professor, Dermatology Dept., Graduate School of Medicine, Hokkaido University
  2021 Feb Senior associate professor, Dermatology Dept., Faculty of Medicine and Graduate School of Medicine Hokkaido University
  2021 Apr Senior associate professor, Research Institute for Electronic Science, Hokkaido University

  Major Publications

  1. Mai Y, Kobayashi Y, Kitahata H, Seo T, Nohara T, Itamoto S, Mai S, Kumamoto J, Nagayama M, Nishie W, Ujiie H, Natsuga K:
     Patterning in stratified epithelia depends on cell-cell adhesion.
     Life Sci Alliance 7: e202402893, 2024.
  2. Natsuga K, Furuta Y, Takashima S, Nohara S, Kosumi H, Mai Y, Higashi H, Ujiie H:
     Detection of revertant mosaicism in epidermolysis bullosa through Cas9-targeted long read sequencing.
     Hum Mutat 43: 529-536, 2022.
  3. Wang Y, Kitahata H, Kosumi H, Watanabe M, Fujimura Y, Takashima S, Osada SI, Hirose T, Nishie W, Nagayama M, Shimizu H, Natsuga K:
     Collagen XVII deficiency alters epidermal patterning.
     Lab Invest 102: 581-588, 2022.
  4. Kosumi H, Watanabe M, Shinkuma S, Fujimura Y, Tsukiyama T, Donati G, Iwata H, Ujiie H, Natsuga K:
     Wnt/beta-catenin signaling stabilizes hemidesmosomes in keratinocytes.
     J Invest Dermatol 142: 1576-1586, 2022.
  5. Fujimura Y, Watanabe M, Ohno K, Kobayashi Y, Takashima S, Nakamura H, Kosumi H, Wang Y, Mai Y, Lauria A, Proserpio V, Ujiie H, Iwata H, Nishie W, Nagayama M, Oliviero S, Donati G, Shimizu H, Natsuga K:
     Hair follicle stem cell progeny heal blisters while pausing skin development.
     EMBO Rep 22: e50882, 2021.
  6. Watanabe M, Natsuga K, Nishie W, Kobayashi Y, Donati G, Suzuki S, Fujimura Y, Ujiie H, Shinkuma S, Nakamura H, Murakami M, Ozaki M, Nagayama M, Watt FM, Shimizu H:
     Type XVII collagen coordinates proliferation in the interfollicular epidermis.
     Elife 6: e26635, 2017.
  7. Natsuga K, Cipolat S, Watt FM:
     Increased bacterial load and expression of antimicrobial peptides in skin of barrier-deficient mice with reduced cancer susceptibility.
     J Invest Dermatol 136: 99-106, 2016.
  8. Natsuga K, Nishie W, Shinkuma S, Ujiie H, Nishimura M, Sawamura D, Shimizu H:
     Antibodies to pathogenic epitopes on type XVII collagen cause skin fragility in a complement-dependent and -independent manner.
     J Immunol 188: 5792-5799, 2012.
  9. Natsuga K, Nishie W, Smith BJ, Shinkuma S, Smith TA, Parry DA, Oiso N, Kawada A, Yoneda K, Akiyama M, Shimizu H:
     Consequences of two different amino-acid substitutions at the same codon in KRT14 endicate definitive roles of structural distortion in epidermolysis bullosa simplex pathogenesis.
     J Invest Dermatol 131: 1869-1876, 2011.
  10. Natsuga K, Nishie W, Akiyama M, Nakamura H, Shinkuma S, McMillan JR, Nagasaki A, Has C, Ouchi T, Ishiko A, Hirako Y, Owaribe K, Sawamura D, Bruckner-Tuderman L, Shimizu H:
      Plectin expression patterns determine two distinct subtypes of epidermolysis bullosa simplex.
      Hum Mutat 31: 308-316, 2010.

  Publication Lists (PubMed)

• WATANABE Mika

  Associate professor

  Fields of specialty

  Wound healing, Epidermal stem cells, Epidermolysis bullosa

  More

  Certification

  Board Certification by Japanese Dermatological Association

  Professional Societies

  The Japanese Dermatological Association
  The Japanese Society for Investigative Dermatology (Guideline Committee Member)
  Japanese Society for Psoriasis Research
  Japan Organization of Clinical Dermatologists
  European Society for Dermatological Research

  Education and professional experience

  2007 Mar　M.D.,Hokkaido University School of Medicine
  2007 Apr　Resident, Tokyo Metropolitan Bokutoh Hospital
  2009 Apr　Medical staff, Dermatology Dept., Hokkaido Univ. Hospital
  2011Apr　Senior Resident, Dermatology Dept., Sapporo City General Hospital
  2012 Apr　Medical staff, Dermatology Dept., JR Sapporo Hospital
  2013 Apr　Medical staff, Dermatology Dept., Hokkaido Univ. Hospital
  2017 Dec　Ph.D., Dermatology Dept., Graduate School of Medicine, Hokkaido University
  2018 Apr　Postdoctral researcher, University of Turin, Molecular biotechnology center (Giacomo Donati Lab, Italy)
  2019 Apr    JSPS Overseas Research Fellowship
  2023 Jan   Assistant Professor, Dermatology Dept., Hokkaido Univ. Hospital
  2024 Jan   Associate Professor, Dermatology Dept., Hokkaido Univ. Hospital

  Major Publications

  1. Levra levron C†, Watanabe M†, Proserpio V† (†: co-first authors), Piacenti G, Lauria A, Kaltenbach S, Tamburrini A, Nohara T, Anselmi F, Duval C, Elettrico L, Donna D, Conti L, Baev D, Natsuga K, Hagai T, Oliviero S, Donati G:
     Tissue memory relies on stem cell priming in distal undamaged areas.
     Nat Cell Biol, 25: 740–753, 2023.
  2. Kosumi H, Watanabe M, Shinkuma S, Nohara T, Fujimura Y, Tsukiyama T, Donati G, Iwata H, Nakamura H, Ujiie H, Natsuga K:
     Wnt/β-catenin signaling stabilizes hemidesmosomes in keratinocytes.
     J Invest Dermatol, 142: 1576-158, 2022.
  3. Wang Y, Kitahata H, Kosumi H, Watanabe M, Fujimura Y, Takashima S, Osada S-I, Hirose T, Nishie W, Nagayama M, Shimizu H, Natsuga K:
     Collagen XVII deficiency alters epidermal patterning.
     Lab Invest, 102: 581–588, 2022.
  4. Watanabe M, Kosumi H, Osada S-I, Takashima S, Wang Y, Nishie W, Oikawa T, Hirose T, Shimizu H, Natsuga K:
     Type XVII collagen interacts with the aPKC‐PAR complex and maintains epidermal cell polarity.
     Exp Dermatol, 30: 62–67,2021.
  5. Fujimura Y, Watanabe M, Ohno K, Kobayashi Y, Takashima S, Nakamura H, Kosumi H, Wang Y, Mai Y, Lauria A, Proserpio V, Ujiie H, Iwata H, Nishie W, Nagayama M, Oliviero S, Donati G, Shimizu H, Natsuga K:
     Hair follicle stem cell progeny heal blisters while pausing skin development.
     EMBO Rep, 22: e50882, 2021.
  6. Watanabe M, Natsuga K, Shinkuma S, Shimizu H:
     Epidermal aspects of type VII collagen: implications for dystrophic epidermolysis bullosa and epidermolysis bullosa acquisita.
     J Dermatol, 45: 515-521, 2018.
  7. Kosumi H, Watanabe M, Natsuga K, Miyauchi T, Shiiya C, Ujiie H, Shimizu H:
     Sweet’s syndrome mimicking ANCA-associated vasculitis.
     Am J Med, 131: e241-e242, 2018.
  8. Watanabe M, Natsuga K, Nishie W, Kobayashi Y, Donati G, Suzuki S, Fujimura Y, Ujiie H, Shinkuma S, Nakamura H, Murakami M, Ozaki M, Nagayama M, Watt FM, Shimizu H:
     Type XVII collagen coordinates proliferation in the interfollicular epidermis.
     ELife, 6: e26635, 2017.
  9. Hayashi R, Natsuga K, Watanabe M, Iwata H, Shinkuma S, Ito A, Masui Y, Ito M, Shimomura Y:
     Epidermolysis bullosa acquisita develops in dominant dystrophic epidermolysis bullosa.
     J Invest Dermatol, 136:320-3, 2016.
  10. Watanabe M, Ujiie H, Nishimura K, Kamiyama T, Abe R, Shimizu H:
      Mycosis fungoides associated with splenic infarction and muscle involvement.
      Br J Dermatol, 173; 1100-1102, 2015.

  Publication Lists (PubMed)

• ITO Takamasa

  Assistant professor

  Fields of specialty

  Skin immunology, Drug eruption

  More

  Certification

  Board Certification by Japanese Dermatological Association

  Professional Societies

  The Japanese Dermatological Association
  The Japanese Society for Investigative Dermatology
  Japan Organization of Clinical Dermatologists

  Education and professional experience

  2010　M.D.,Hokkaido University School of Medicine
  2010　Resident, Chigasaki Tokushukai General Hospital
  2012　Medical staff, Dermatology Dept., Hokkaido Univ. Hospital
  2013　Senior Resident, Dermatology Dept., Sapporo City General Hospital
  2015　Medical staff, Dermatology Dept., Hokkaido Univ. Hospital
  2018　Ph.D., Dermatology Dept., Graduate School of Medicine, Hokkaido University
  2019　Department director, Dermatology Dept., Tonan hospital
  2020　Postdoctral fellow, Columbia University, The department of  microbiology and immunology (Huang Yuefeng Lab, USA)
  2022    JSPS Overseas Research Fellowship
  2024　Assistant Professor, Dermatology Dept., Hokkaido Univ. Hospital

  Publication Lists (PubMed)

• MURAMATSU Ken

  Assistant professor

  Fields of specialty

  Autoimmune blistering diseases, Skin immunology

  More

  Certification

  Board Certification by Japanese Dermatological Association
  Board Certification by Japanese Association for Medical Artificial Intelligence

  Professional Societies

  The Japanese Dermatological Association
  The Japanese Society for Investigative Dermatology
  The Japanese Association for Medical Artificial Intelligence

  Education and professional experience

  2011 Mar　M.D.,Hokkaido University School of Medicine
  2011 Apr　Junior Resident, Hokkaido Univ. Hospital
  2012 Apr　Junior Resident, Obihiro Kosei Hospital
  2013 Apr　Senior Resident, Dermatology Dept., Hokkaido Univ. Hospital
  2014 Apr　Senior Resident, Dermatology Dept., KKR Sapporo Medical Center
  2019 Mar　Ph.D., Dermatology Dept., Graduate School of Medicine, Hokkaido University
  2019 Apr　Medical Staff, Dermatology Dept., JR Sapporo Hospital
  2020 Apr　Medical Staff, Dermatology Dept., Kushiro City General Hospital
  2020 Jul　Medical Staff, Dermatology Dept., Hokkaido Univ. Hospital
  2021 Oct Research Fellow, Agency for Science, Technology and Research（Florent GINHOUX Lab, Singapore）
  2022 Oct JSPS Overseas Research Fellowship (Agency for Science, Technology and Research)
  2023 Nov Assistant Professor, Dermatology Dept., Hokkaido Univ. Hospital

  Major Publications

  1. Kawamura T, Muramatsu K, Orita A, Mai Y, Sugai T, Haga N, Fujimura Y, Miyauchi T, Izumi K, Koga H, Ishii N, Ujiie H:
     Two cases of Hallopeau-type pemphigus vegetans with anti-desmoglein 1 and anti-desmocollin 3 antibodies without mucosal involvement.
     J Eur Acad Dermatol Venereol 37: e508-e510, 2023.
  2. Ozeki T, Muramatsu K, Yoshimoto N, Ujiie I, Izumi K, Iwata H, Mushiroda T, Ujiie H:
     Association of Genetic Variants of HLA-DQA1 with Bullous Pemphigoid Induced by Dipeptidyl Peptidase-4 Inhibitors.
     J Invest Dermatol 143: 2219-2225.e5, 2023.
  3. Muramatsu K, Zheng M, Yoshimoto N, Ito T, Ujiie I, Iwata H, Shimizu H, Ujiie H:
     Regulatory T cell subsets in bullous pemphigoid and dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid.
     J Dermatol Sci 100: 23-30, 2020.
  4. Muramatsu K, Ujiie H, Kobayashi I, Nishie W, Izumi K, Ito T, Yoshimoto N, Natsuga K, Iwata H, Shimizu H:
     Regulatory T-cell dysfunction induces autoantibodies to bullous pemphigoid antigens in mice and human subjects.
     J Allergy Clin Immunol 142: 1818-1830.e6, 2018.
  5. Ujiie H, Muramatsu K, Mushiroda T, Ozeki T, Miyoshi H, Iwata H, Nakamura A, Nomoto H, Cho KY, Sato N, Nishimura M, Ito T, Izumi K, Nishie W and Shimizu H:
     HLA-DQB1*03:01 as a biomarker for susceptibility to bullous pemphigoid induced by DPP-4 inhibitor.
     J Invest Dermatol 138: 1201-1204, 2018.
  6. Muramatsu K, Ujiie H, Shimizu H:
     Postherpetic abdominal pseudohernia.
     BMJ 358: j2786, 2017.
  7. Muramatsu K, Ujiie H, Natsuga K, Nishie W, Shimizu H:
     Lichenoid drug eruption caused by clonazepam.
     J Eur Acad Dermatol Venereol 31: e117-e118, 2017.
  8. Muramatsu K, Nishie W, Natsuga K, Fujita Y, Iwata H, Yamada T, Yamashita E, Asaka T, Shimizu H:
     Two cases of erosive oral lichen planus with autoantibodies to desmoglein 3.
     J Dermatol 43: 1350-1353, 2016.
  9. Muramatsu K, Fujita Y, Inokuma D, Tsukinaga I, Ito K, Nishiura Y, Shimizu H:
     Cutaneous Manifestations of Thymoma-associated Multi-organ Autoimmunity: A Fatal Sign.
     Acta Dermato-Venereol 96: 818-819, 2016.
  10. Muramatsu K, Nomura T, Ito T, Hamade Y, Hirata Y, Fujita Y, Abe R, Shimizu H:
      Repeated skin sampling and prolonged incubation period identified cutaneous Mycobacaterium chelonae infection on the face in an immunocompetent man.
      Br J Dermatol 170: 471-473, 2014.

  Publication Lists (PubMed)

• TAKASHIMA Shota

  Assistant professor

  Fields of specialty

  Genetic skin diseases, Epidermolysis bullosa

  More

  Certification

  Board Certification by Japanese Dermatological Association

  Professional Societies

  The Japanese Dermatological Association
  The Japanese Society for Investigative Dermatology
  Society for Investigative Dermatology

  Education and professional experience

  2012 Mar　M.D.,Hokkaido University School of Medicine
  2012 Apr　Junior Resident, Kushiro Red Cross Hospital
  2013 Apr　Junior Resident, Hokkaido Univ. Hospital
  2014 Apr　Medical staff, Chitose City Hospital
  2015 Apr　Medical staff, Dermatology Dept., Hokkaido Univ. Hospital
  2018 Apr　Medical staff, Chitose City Hospital
  2019 Jun　Ph.D., Dermatology Dept., Graduate School of Medicine, Hokkaido University
  2020 Jul　Visiting Scholar, Dermatology Dept., University of California, San Diego (Bryan Sun lab., U.S.A)
  2022 Aug Assistant Professor, Dermatology Dept., Faculty of Medicine and Graduate School of Medicine Hokkaido University

  Major Publications

  1. Takashima S, Shinkuma S, Fujita Y, Nomura T, Ujiie H, Natsuga K, Iwata H, Nakamura H, Vorobyev A, Abe R, Shimizu H:
     Efficient reframing gene therapy for recessive dystrophic epidermolysis bullosa with CRISPR/Cas9.
     J Invest Dermatol 139, 1711-1721, 2019.
  2. Natsuga K, Furuta Y, Takashima S, Nohara T, Kosumi H, Mai Y, Higashi H, Ujiie H:
     Detection of revertant mosaicism in epidermolysis bullosa through Cas9-targeted long-read sequencing.
     Hum Mutat 43: 529-536, 2022.
  3. Takashima S, Fujita Y, Saito N, Suzuki S, Nomura T, Shimizu H:
     RNA recognition motif of LEMD3 as a key player in the pathogenesis of Buschke-Ollendorff syndrome.
     J Dermatol Sci 81: 205-208, 2016.
  4. Takashima S, Fujita Y, Shinkuma S, Shimizu S, Hasegawa T, Amizuka N, Shimizu H, Natsuga K*:
     Calcinosis cutis in self-healing dominant dystrophic epidermolysis bullosa.
     J Dermatol 47 :e457-8, 2020.
  5. Matsumura W, Fujita Y, Shinkuma S, Suzuki S, Yokoshiki S, Goto H, Hayashi H, Ono K, Inoie M, Takashima S, Nakayama C, Nomura T, Nakamura H, Abe R, Sato N, Shimizu H:
     Cultured epidermal autografts from clinically revertant skin as a potential wound treatment for recessive dystrophic bullosa.
     J Invest Dermatol 139: 2115-24, 2019.
  6. Takashima S, Shinkuma S, Fujita Y, Nomura T, Hida T, Ishikawa S, Nakamura H, Abe R, Shimizu H:
     A novel COL7A1 mutation in a Japanese family with bullous dermolysis of the newborn: Phenotypic variability associated with a COL7A1 mutation within the same family.
     J Dermatol 34: e260-1, 2018.
  7. Takashima S, Nishie W, Morita Y, Osawa R, Iwata H, Fujita Y, Fujimoto K, Shimizu H:
     Eosinophilic pustular folliculitis in a patient with mycosis fungoides.
     J Eur Acad Dermatol Venereol 30: 712-3, 2016.
  8. Takashima S, Iwata H, Sakata M, Osawa R, Nishie W, Shimizu H:
     Widespread erythema ab igne caused by hot bathing.
     J Eur Acad Dermatol Venereol 29: 2259-61, 2015.
  9. Takashima S，Fujita Y，Miyauchi T，Nomura T，Nishie W，Hamaoka S, Shimizu H:
     Dermoscopic observation in adenoma of the nipple.
     J Dermatol 42: 341-2, 2015.
  10. Takashima S, Sakamoto T, Ota M:
      Tumoral calcinosis in chronic renal failure.
      Lancet Diabetes Endocrinol 2: 852, 2014.

  Publication Lists (PubMed)

• MAEDA Takuya

  Assistant professor

  Fields of specialty

  Skin cancer, Dermatologic surgery

  More

  Certification

  Board Certification by Japanese Dermatological Association

  Professional Societies

  The Japanese Dermatological Association
  Japanese Skin Cancer Society
  The Japanese Society for Investigative Dermatology
  Japan Organization of Clinical Dermatologists

  Education and professional experience

  2015 Mar　M.D.,Hokkaido University School of Medicine
  2015 Apr　Resident, Kitami Red cross Hospital
  2016 Apr　Resident, Hokkaido Univ. Hospital
  2017 Apr    Medical staff, Dermatology Dept., Hokkaido Univ. Hospital
  2018 Apr  Medical staff, Dermatologic Oncology Dept., Tokyo metropolitan Cancer and infectious disease center Komagome Hospital
  2019  Apr　Medical staff, Dermatology Dept., Hokkaido Univ. Hospital
  2021 Apr  Medical staff, Dermatologic Oncology Dept., Tokyo metropolitan Cancer and infectious disease center Komagome Hospital
  2022 Apr    Medical staff, Dermatology Dept., Hokkaido Univ. Hospital
  2023 Mar   Ph.D., Dermatology Dept., Graduate School of Medicine, Hokkaido University
  2023 Jul      Assistant Professor, Dermatology Dept., Hokkaido Univ. Hospital

  Major Publications

  1. Maeda T, Hiura A, Uehara J, Toyoshima R, Nakagawa T, Yoshino K:
     Early tumor response assessment may avoid serious immune-related adverse events in nivolumab and ipilimumab combination therapy for stage IV melanoma.
     Br J Dermatol 186: 587-588, 2022.
  2. Maeda T, Hiura A, Uehara J, Toyoshima R, Nakagawa T, Yoshino K:
     Neutrophil-to-lymphocyte ratio is associated with survival and sentinel lymph node positivity in invasive cutaneous squamous cell carcinoma: A retrospective study.
     J Am Acad Dermatol 86: 615-620, 2022.
  3. Maeda T, Hiura A, Uehara J, Toyoshima R, Nakagawa T, Yoshino K:
     Combined carboplatin and paclitaxel therapy improves overall survival in patients with nivolumab-resistant acral and mucosal melanoma.
     Br J Dermatol 186: 361-363, 2022.
  4. Maeda T, Kitamura S, Yanagi T:
     RANK-RANKL signaling pathway contributes to disease progression in cutaneous angiosarcoma: A case report with an immunohistochemical review and in vitro experiments.
     J Eur Acad Dermatol Venereol 34: e834-e837, 2020.
  5. Maeda T, Kitamura S, Nishihara H, Yanagi T:
     Extramammary Paget’s disease patient-derived xenografts harboring ERBB2 S310F mutation show sensitivity to HER2-targeted therapies.
     Oncogene 39: 5867-5875, 2020.
  6. Maeda T, Yoshino K, Nagai K, Oaku S, Kato M, Hiura A, Fujisawa Y:
     The effect of the lymphovascular plugging metastasis pattern in extramammary Paget’s disease on identifying metastatic lesions by imaging tests: an autopsy case series.
     Br J Dermatol 182: 493-495, 2020.
  7. Maeda T, Yoshino K, Nagai K, Oaku S, Kato M, Hiura A, Hata H:
     Development of endocrine immune-related adverse events and improved survival in advanced melanoma patients treated with nivolumab monotherapy.
     Eur J Cancer 115: 13-16, 2019.
  8. Maeda T, Yoshino K, Nagai K, Oaku S, Kato M, Hiura A, Hata H:
     Efficacy of nivolumab monotherapy against acral lentiginous melanoma and mucosal melanoma in Asian patients.
     Br J Dermatol 180: 1230-1231, 2019.
  9. Hiura A, Yoshino K, Maeda T, Nagai K, Oaku S, Kato M, Fujisawa Y:
     Chemoradiotherapy could improve overall survival of patients with stage IV cutaneous squamous cell carcinoma: analysis of 34 cases.
     Br J Dermatol 180: 1557-1558, 2019.
  10. Kato M, Yoshino K, Maeda T, Nagai K, Oaku S, Hiura A, Fujisawa Y:
      Single-agent taxane is useful in palliative chemotherapy for advanced extramammary Paget’s disease; A Case Series.
      Br J Dermatol 181: 831-832, 2019.

  Publication Lists (PubMed)

Medical Staffs / Residents / Visiting Clinical Doctors

• UJIIE Inkin
• TOKUCHI Keiko

  1030

• HASE Takahiro
• HIKICHI Shiori
• TANAKA Arisa
• YAMAGA Misako
• NARUSE Satsuki
• UENO Shoko
• OIKAWA Asuka
• SATO Soma
• WATANABE Kazuki
• WATANABE Yukako

Ph.D. Course Students

• PEH Jin Teng
• TAKEDA Masae
• SHIIYA Chihiro
• NOHARA Takuma
• HSU Che-yuan
• SEO Takashi
• KATAYAMA Sho
• MIYAMOTO Kodai
• KAWAMURA Takuya
• INAMURA Emi
• MIZUKAMI Takuya
• SHIMANO Mayuna
• KIMURA Ayame
• HIRANO Yoko
• HAYASHIBE Ruri
• TRAJKOVIC Gabriel

Researchers

• YANAGI Teruki
• IZUMI Kentaro
• MAI Shoko

Central Research Institute

• NAKAMURA Hideki

Researching Abroad

• MIYAUCHI Toshinari
• IMAFUKU Keisuke
• KOSUMI Hideyuki
• MAI Yosuke

Laboratory Technicians

• AOKI Kumiko
• KATO Sora

Medical Secretaries

• ISHIKAWA Chieko
• HATAKEYAMA Miho

Secretaries

• OSUMI Maki
• TOSHIRO Naoko
• ARISAKA Tomoe
• INADA Keiko

On leave of absence

• TOYONAGA Ellen

Professor Emeritus

• OHKAWARA Akira

Visiting Professor

• NOMURA Toshifumi

Assistant Adjunct Professors

• KUMAKIRI Masanobu
• MATSUMURA Kazuko
• SHIMIZU Satoko
• KODAMA Kazuo
• NAKAMURA Hiroyuki
• ITO Kei
• OTA Mitsuhito
• HOSHINA Daichi
• ANAN Takashi
• SUZUKI Shotaro
• FUJITA Yasuyuki
• FUJIMURA Yu
• HOTTA Moeko
• NOMURA Toshifumi
• IWATA Hiroaki
• ANDO Satomi
• KIKUCHI Kazuhiro
• MIYAZAWA Hajime　
• YAMAGUCHI Yasuyuki